Characterisation of kinin receptors on the human isolated umbilical artery
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چکیده
منابع مشابه
Noscapine antagonizes vasoconstrictor action of bradykinin in isolated human umbilical artery
Abstract Background: It has been demonstrated that noscapine, an antitussive opioid alkaloid, could antagonize bradykinin- induced responses such as bradykinin effects in guinea-pig ileum, cough induced by bradykinin receptor agonist and angiotensin converting enzyme inhibitors, and brain damage after brain edema both in neonatal rat model and in patients with stroke. In the present study, the...
متن کاملCharacterization of receptors involved in serotonin contractions of isolated human umbilical artery in uncomplicated pregnancy
Background Serotonin (5-HT), is a vasoactive substance involved in physiological functioning of fetoplacental blood flow and continuous modulation of smooth muscle tone in umbilical vein and arteries. Since umbilical blood vessels have been shown to be deficient in autonomic innervation, the action of local autocrine vasoactive substances (including serotonin) is of considerable importance. Alt...
متن کاملIsolated single umbilical artery and fetal karyotype.
OBJECTIVE To determine the need for fetal karyotyping in cases of an isolated single umbilical artery (SUA) identified during the second-trimester routine anomaly scan. METHODS All patients booked for antenatal care and delivery in our hospital are offered two ultrasound scans in pregnancy, one at 11-13 weeks' gestation as part of screening for chromosomal defects and another at 20-23 weeks f...
متن کاملThe effects of bumetanide on human umbilical artery contractions.
The authors investigate the effect of bumetan ide, an inhibitor of NKCC1 and a loop diuretic, on the tone of human umbilical artery (HUA). Rings of HUA (n = 35) from vaginal deliveries were suspended for isometric tension recordings in organ baths. Cumulative concentration-response curves to serotonin, histamine, and KCl were performed in the absence (control) or in the presence of bumetanide. ...
متن کاملThe Effect of mode of delivery on the umbilical artery pH
Background: Abnormal umbilical cord pH can be indicated a distress imposed of newborn and can also be useful in determining the prognosis of the newborn. There are different views about the effect of the neonatal delivery method on the blood gas analysis of the umbilical artery. This study aimed to determine the effect of the method of delivery on umbilical artery pH. Methods: In this Cross ...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 1998
ISSN: 0022-0795,1479-6805
DOI: 10.1677/joe.0.1560389